Search results for "Elimination diet"

showing 10 items of 12 documents

Oral cromolyn sodium in comparison with elimination diet in the irritable bowel syndrome, diarrheic type. Multicenter study of 428 patients.

1995

In a significant number of patients affected by the irritable bowel syndrome, an adverse reaction to food is proposed to be a causative factor. A diet that eliminates the offending foods is the obvious treatment for such adverse reactions. Compliance with a dietetic regimen is often poor and sometimes not completely free from risks.Since the diarrheic type of irritable bowel syndrome seems mainly affected by food intolerance, and previous observations suggested that oral cromolyn sodium is effective in such patients, a multicenter therapeutic trial in the diarrheic type of irritable bowel syndrome was carried out in 346 of 409 patients with this disease, to evaluate the effects of oral crom…

AdultDiarrheaMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentAdministration OralColonic Diseases FunctionalGastroenterologyOral administrationInternal medicineElimination dietAnti-Allergic AgentsCromolyn SodiummedicineHumansAdverse effectIrritable bowel syndromeAgedAged 80 and overChemotherapybusiness.industrydigestive oral and skin physiologyGastroenterologyCromolyn SodiumMiddle Agedmedicine.diseasePrognosisDiarrheaTreatment OutcomeMulticenter studyFemalemedicine.symptombusinessFood HypersensitivityScandinavian journal of gastroenterology
researchProduct

A comparison between two different in vitro basophil activation tests for gluten- and cow's milk protein sensitivity in irritable bowel syndrome (IBS…

2013

Abstract Background: The diagnosis of food hypersensitivity (FH) in adult patients with gastrointestinal symptoms, beyond the immediate IgE-mediated clinical manifestations, is very often difficult. The aims of our study were to: 1) evaluate the frequency of FH in patients with irritable bowel syndrome (IBS)-like clinical presentation; and 2) compare the diagnostic accuracy of two different methods of in vitro basophil activation tests. Methods: Three hundred and five patients (235 females, age range 18–66 years) were included and underwent a diagnostic elimination diet and successive double-blind placebo-controlled (DBPC) challenges. Two different methods of in vitro basophil activation te…

AdultMaleSettore MED/09 - Medicina InternaAdolescentGlutensClinical Biochemistrygluten-sensitivityIrritable Bowel SyndromeYoung AdultElimination dietMedicineHumansYoung adultIrritable bowel syndromeTriticumWhole bloodAgedchemistry.chemical_classificationCD63business.industryBiochemistry (medical)General MedicineMiddle Agedmedicine.diseaseMilk ProteinsGlutenIn vitroBasophilsBasophil activationCeliac Diseasebasophil activation test; gluten-sensitivity; irritable bowel syndromechemistrybasophil activation testImmunologyFemaleMilk Hypersensitivitybusiness
researchProduct

A Cytologic Assay for Diagnosis of Food Hypersensitivity in Patients With Irritable Bowel Syndrome

2010

BACKGROUND & AIMS: A percentage of patients with symptoms of irritable bowel syndrome (IBS) suffer from food hypersensitivity (FH) and improve on a food-elimination diet. No assays have satisfactory levels of sensitivity for identifying patients with FH. We evaluated the efficacy of an in vitro basophil activation assay in the diagnosis of FH in IBS-like patients. METHODS: Blood samples were collected from 120 consecutive patients diagnosed with IBS according to Rome II criteria. We analyzed in vitro activation of basophils by food allergens (based on levels of CD63 expression), as well as total and food-specific immunoglobulin (Ig)E levels in serum. Effects of elimination diets and dou…

AdultMalefood hypersensitivitySettore MED/09 - Medicina InternaAdolescentCytologic assay; food hypersensitivity; irritable bowel diseaseCytological Techniquesirritable bowel diseasePlatelet Membrane GlycoproteinsImmunoglobulin ESensitivity and SpecificityIrritable Bowel SyndromeYoung AdultAntigenAntigens CDElimination dietmedicineAnimalsHumansYoung adultCells CulturedIrritable bowel syndromeCytologic assayHepatologybiologyCD63Tetraspanin 30business.industryGastroenterologyAllergensImmunoglobulin EMiddle Agedmedicine.diseaseBasophilsBasophil activationImmunologybiology.proteinFemaleAntibodybusinessClinical Gastroenterology and Hepatology
researchProduct

Abdominal Ultrasound Does Not Reveal Significant Alterations in Patients With Nonceliac Wheat Sensitivity

2017

Abstract GOALS: The goal of this study was (A) to evaluate abdominal ultrasound signs in nonceliac wheat sensitivity (NCWS) patients for features useful in diagnosis and (B) to compare these aspects with those of celiac patients to assess whether ultrasound can be useful in the differential diagnosis between NCWS and celiac disease (CD). BACKGROUND: NCWS diagnosis is difficult as no biomarkers of this condition have as yet been identified. In CD ultrasound aspects have been identified that have a good diagnostic accuracy. STUDY: We prospectively recruited 45 NCWS patients (11 males, 34 females; mean age 35.7 y). Three control groups were included: (A) 99 age-matched CD patients; (B) 18 pati…

AdultMalemedicine.medical_specialtyNon-Celiac Wheat sensitivity Celiac Disease Abdominal Ultrasound Seronegative celiac disease Double-blind placebo-controlled challengeSettore MED/09 - Medicina InternaGlutensWheat HypersensitivityGastroenterology030218 nuclear medicine & medical imagingDiagnosis DifferentialIrritable Bowel SyndromeDiet Gluten-FreeYoung Adult03 medical and health sciences0302 clinical medicineDouble-Blind MethodInternal medicineElimination dietAbdomenAscitesmedicineHumansMesenteric lymph nodesProspective StudiesProspective cohort studyIrritable bowel syndromeUltrasonographybusiness.industryUltrasoundGastroenterologyMiddle Agedmedicine.diseaseCeliac Diseasemedicine.anatomical_structureFemale030211 gastroenterology & hepatologyGluten freemedicine.symptomDifferential diagnosisbusiness
researchProduct

Fecal assays detect hypersensitivity to cow's milk protein and gluten in adults with irritable bowel syndrome.

2011

Background & Aims Some patients with irritable bowel syndrome (IBS)-like symptoms suffer from food hypersensitivity (FH); their symptoms improve when they are placed on elimination diets. No assays identify patients with FH with satisfactory levels of sensitivity. We determined the frequency of FH among patients with symptoms of IBS and the ability of fecal assays for tryptase, eosinophil cationic protein (ECP), or calprotectin to diagnose FH. Methods The study included 160 patients with IBS, 40 patients with other gastrointestinal diseases, and 50 healthy individuals (controls). At the start of the study, patients completed a symptom severity questionnaire, fecal samples were assayed, and …

AdultMalemedicine.medical_specialtySettore MED/09 - Medicina InternaFecal Calprotectin.AdolescentGlutensTryptaseWheat HypersensitivityGastroenterologyIrritable Bowel SyndromePlacebosFecesYoung Adultfluids and secretionsDouble-Blind MethodInternal medicineElimination dietmedicineHumansIrritable bowel syndromeFeceschemistry.chemical_classificationEosinophil cationic proteinHepatologybiologybusiness.industryOral food challengeEosinophil Cationic ProteinGastroenterologyMiddle Agedmedicine.diseaseGlutenDietchemistryGluten SensitivityImmunologybiology.proteinFemaleTryptasesCalprotectinCow’s Milk Protein HypersensitivityMilk HypersensitivitybusinessLeukocyte L1 Antigen ComplexCow’s Milk Protein Hypersensitivity; Gluten Sensitivity; Fecal Tryptase; Fecal Eosinophil Cationic Protein; Fecal Calprotectin.Fecal TryptaseFecal Eosinophil Cationic ProteinClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
researchProduct

Risk of low bone mineral density and low body mass index in patients with non-celiac wheat-sensitivity: a prospective observation study.

2014

Background Non-celiac gluten sensitivity (NCGS) or ‘wheat sensitivity’ (NCWS) is included in the spectrum of gluten-related disorders. No data are available on the prevalence of low bone mass density (BMD) in NCWS. Our study aims to evaluate the prevalence of low BMD in NCWS patients and search for correlations with other clinical characteristics. Methods This prospective observation study included 75 NCWS patients (63 women; median age 36 years) with irritable bowel syndrome (IBS)-like symptoms, 65 IBS and 50 celiac controls. Patients were recruited at two Internal Medicine Departments. Elimination diet and double-blind placebo controlled (DBPC) wheat challenge proved the NCWS diagnosis. A…

AdultRiskmedicine.medical_specialtySettore MED/09 - Medicina InternaBone densityGlutensNon-celiac wheat sensitivityOsteoporosisGastroenterologyBody Mass IndexIrritable Bowel SyndromeYoung AdultDouble-Blind MethodBone DensityInternal medicineElimination dietmedicinePrevalenceHumansMultiple food allergyProspective StudiesProspective cohort studyIrritable bowel syndromeBone mineralMedicine(all)business.industryGeneral MedicineMiddle Agedmedicine.diseaseOsteopeniaBone Diseases MetabolicCeliac DiseaseIntestinal DiseasesEndocrinologyOsteoporosisnon-celiac wheat-sensitivityFemalebone mineral density; body mass index; non-celiac wheat-sensitivitybusinessbone mineral densityBody mass indexResearch ArticleBMC medicine
researchProduct

Sensitization in early age to food allergens in children with atopic dermatitis

2007

Background: Clinical and laboratory evidence increasingly supports the notion that food allergy plays a role in the pathogenesis of atopic dermatitis (AD). However, the prevalence of clinically significant food hypersensitivity among children with AD remains an unanswered question. Objective: To prospectively determine the prevalence of IgE-mediated food hypersensitivity among patients referred to a dermatology department for evaluation of AD, and to analyze the clinical relevance of these sensitizations in AD. Methods: We studied 44 infants of both sexes, aged less than 12 months old, who attended the dermatology department with symptoms of AD. Compliance with Hanifin-Rajka criteria was co…

MalePulmonary and Respiratory Medicinefood hypersensitivitymedicine.medical_specialtyEggsImmunologyEgg Proteins DietarySeverity of Illness IndexDermatitis Atopicfood challengeAntibody SpecificityFood allergyElimination dietPrevalencemedicineAnimalsHumansImmunology and AllergyClinical significanceProspective StudiesAge of OnsetFood allergensSensitizationSkin Testsfood allergyatopic dermatitisbusiness.industryInfantegg allergyGeneral MedicineAtopic dermatitisAllergensImmunoglobulin EMilk Proteinsmedicine.diseaseFood hypersensitivityDermatologycow's milk allergymedicine.anatomical_structureEgg allergyCattleFemaleInfant FoodMilk HypersensitivitybusinessChickensFood Hypersensitivity
researchProduct

Multiple food hypersensitivity as a cause of refractory chronic constipation in adults

2006

Chronic constipation that is unresponsive to laxative treatment is a severe illness, but children unresponsive to laxatives have been successfully treated with an elimination diet. We report the first cases of refractory chronic constipation caused by food hypersensitivity in adults. Four patients with refractory constipation who were unresponsive to high doses of laxatives were put on an oligo-antigenic diet and underwent successive double-blind, placebo-controlled, food challenges (DBPFC). Routine laboratory tests, immunological assays, colonoscopy, esophago-gastroduodenoscopy and rectal and duodenal histology were performed. While on an elimination diet, bowel habits normalized in all pa…

Malemedicine.medical_specialtyAbdominal painConstipationmedicine.medical_treatmentLaxativeRectumChronic constipation diet duodenal histology food hypersensitivity rectal histologyGastroenterologyHemoglobinsLeukocyte CountDouble-Blind MethodInternal medicineElimination dietmedicineHumansIntestinal MucosaAgedRetrospective StudiesChronic constipationbusiness.industryGastroenterologyMiddle Agedmedicine.diseaseFood intolerancemedicine.anatomical_structureChronic DiseaseFemalemedicine.symptombusinessConstipationFood HypersensitivityFollow-Up StudiesAnal itchingScandinavian Journal of Gastroenterology
researchProduct

A Popular myth - low-histamine diet improves chronic spontaneous urticaria - fact or fiction?

2016

Background Chronic spontaneous urticaria (CsU) is a frequent dermatological disease that might last for months or years with high impact on quality of life. Known causes are autoreactive phenomena, infections or intolerances, rarely IgE-mediated allergies. One third of CsU patients benefit from a low-pseudoallergen diet. Additionally, it is often discussed, that reducing histamine ingestion alone might improve clinical symptoms and quality of life in CsU-patients despite the uncertain role of the histamine-degrading enzyme diamine oxidase (DAO). Objective Aim of this study is to investigate the impact of low-histamine diet on symptoms and quality of life in patients with CsU. Methods Patien…

Malemedicine.medical_specialtyAllergyUrticariaDermatologySeverity of Illness Index030207 dermatology & venereal diseases03 medical and health sciences0302 clinical medicineIntolerancesQuality of lifeSurveys and QuestionnairesElimination dietInternal medicineSeverity of illnessmedicineClinical endpointHumansIngestionbusiness.industrymedicine.diseaseSurgeryTreatment OutcomeInfectious Diseases030228 respiratory systemChronic DiseaseQuality of LifeFemaleAmine Oxidase (Copper-Containing)Diamine oxidasebusinessHistamineJournal of the European Academy of Dermatology and Venereology
researchProduct

The "red umbilicus": a diagnostic sign of cow's milk protein intolerance

2006

Introduction: Red umbilicus is considered to be an infectious disease typical of neonates. In our experience, umbilical erythema could be due to cow's milk protein intolerance (CMPI). Aims: To evaluate the frequency and clinical significance of umbilical erythema in a series of consecutive children referred for suspected CMPI. Patients and Methods: Seven hundred ninety-six consecutive patients (median age, 18 months) referred for suspected CMPI diagnosis were studied. CMPI diagnosis was based on the disappearance of symptoms on elimination diet and their subsequent reappearance on double-blind placebo-controlled cow's milk challenge. Results: CMPI was diagnosed in 384 patients: 120 with res…

Malemedicine.medical_specialtySettore MED/09 - Medicina InternaErythemaDouble-Blind MethodElimination dietmedicineAnimalsHumansClinical significanceProspective StudiesChildAsthmaUmbilicusMilk proteinbusiness.industryGastroenterologyInfantAtopic dermatitisMilk Proteinsmedicine.diseaseDermatologySurgeryFood intoleranceRed umbilicus; cow's milk protein intolerancecow's milk protein intoleranceErythemaCow's milk proteinChild PreschoolPediatrics Perinatology and Child HealthCattleFemaleMilk Hypersensitivitymedicine.symptombusinessRed umbilicu
researchProduct